The catalog includes cars which have made it to the winner's circle of some of the world's most prestigious concours events, such as a 1939 Mercedes-Benz 540 K Spezial Cabriolet A along with a coveted 1962 Ferrari 400 Superamerica LWB Coupe Aerodinamico.

Also to feature, will be stunning examples of engineering from the Brass Era including a Rolls-Royce 40/50 HP Silver Ghost, to modern exotics such as the 2014 Pagani Huayra.

Gord Duff, Car Specialist, RM Sotheby's comments: "For the collector car community, March is synonymous with the Amelia Island Concours d'Elegance weekend. We're proud to not only be the official auction house of the event, but also one of its longest running sponsors."

"Last year's event was certainly one for the books, launching our new partnership with Sotheby's in spectacular fashion. 12 months on, we've assembled another fantastic group of automobiles with an emphasis on fresh-to-the-market, exquisitely restored examples – a great fit for the concours setting."

The top lot of the is unmistakably a 1939 Mercedes-Benz 540 K Spezial Cabriolet A, chassis no. 408371; a one-off design of excellent provenance The earliest known post-war owner of this 540 K was American operatic tenor James Melton, one of the best known American car collectors of his time. Melton regularly used the Cabriolet A, even recounting with much adoration his adventures with his 'supercharged beast' in his 1954 autobiography, Bright Wheels Rolling. In the 1950's, when Melton began to sell his collection, he held on to the 540 K until 1961, showing just how important the car was to him. The next renowned collector in this 540 K's illustrious history was Otis Chandler, who commissioned an expert restoration, debuting the work to 'Best of Show' honors at the 1973 Pebble Beach Concours d'Elegance. The car later went to such important collectors as Axel Wars and General William Lyon, before it was acquired by the current consigner, who purchased the car over 20 years ago.The bright scarlet car has a tan leather upholstery and a tan cloth top and is expected to excite bidders as the $3 000 000 - $4 000 000 estimate proves.

Jonathan Sierakowski, Car Specialist, RM Sotheby's adds: "This car has all that a superb automobile should have: memorable lines, superb engineering and abundant power. Add in its exceptional ownership chain and its bevy of special one-off features, from the raked vee'd windshield to the louvered front hood, special fitted luggage and the five-speed transmission, a feature only seen on the later examples, and it can be rightfully considered one of the most superlative and unique 540 Ks."

The 1954 Bentley R-Type Continental Fastback Sports Saloon, chassis no. BC2LD is arguably the ultimate R-Type Continental. The magnificent example on offer is completed in the most desirable configuration of factory LHD, 4.9-liter engine, center-shift transmission and the famous "seats and spats". Completed on August 21, 1954, the featured R-Type was shipped from London to New York aboard the SS American Producer and sold to its first owner, Mary Thurston Horn, a member of one of New York's oldest families. The car has had just four private owners from new, and was acquired by its current enthusiast owner in 2009 and promptly restored – the caliber of work honored with a 'Best in Class' at Amelia Island in 2010. It is expected to fetch between $1 200 000 - $1 400 000 in the sale room.

Something for Rolls-Royce enthusiasts, the 1911 Rolls-Royce 40/50 HP Silver Ghost Tourer is one of the most significant "parallel bonnet" Silver Ghosts to come to auction in recent years. The car is one of approximately only 20 surviving examples sporting their original body, engine and chassis. The car boasts an excellent provenance, restoration and show history, including accolades in both AACA National and Rolls-Royce Owners Club competition. The car is estimated to sell for $2 500 000 - $3 500 000.

13 Ferraris will be included in the sale, headlined by the 1962 Ferrari 400 Superamerica LWB Coupe Aerodinamico which is expected to sell for $2 700 000 - $3 300 000.

RM Sotheby's will present a series of charity lots in the Amelia Island Concours d'Elegance sale which will benefit Spina Bifida of Jacksonville.

Search the full sale on Barnebys here.